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Christina C. Wang, M.D., F.R.A.C.P., F.R.C.P. [ Edit Your Profile ]

Email Address: wang@labiomed.org

Fax Number: 310-533-6972
Work Phone Number: 310-222-2503

Mailing Address:
1124 West Carson St., RB-1
Torrance, CA 90502

Office Address:
1000 West Carson Street
Building Room 5L2, Main Unit mail box 16
Torrance, CA 90502

Work
CTSI Associate Director, Site Leader, CTSI Chair, Participant and Clinical Interaction and Resources Program
Harbor UCLA Medical Center Program Director, Harbor UCLA Medical Center
LABioMed Professor, ENDOCRINOLOGY, METABOLISM & NUTRITION
UCLA Professor, Medicine

Research Interests

Medicine - Endocrinology


Education:
Degrees:
F.R.C.P., Royal College of Physicians and Surgeons, Glasgow, U.K, 1988
F.R.A.C.P., Royal Australian College of Physicians, 1974 - 1975
M.D., University of Hong Kong, Hong Kong, 1968 - 1974
B.S., University of Hong Kong, Hong Kong, 1968

Honors and Awards:
2011 American Society of Andrology, Distinguished Service Award

About

Christina Wang, MD is a Professor of Medicine and Assistant Dean in Clinical and Translational Sciences at the David Geffen School of Medicine at UCLA. She is the Associate Director of the UCLA Clinical and Translational Science Institute, and a faculty member of the Division of Endocrinology, Department of Medicine, Harbor-UCLA Medical Center and Los Angeles Biomedical Research Institute (Harbor-UCLA/LA BioMed), Torrance, California. She was a former Professor of Medicine at the University of Hong Kong. She is an internationally renowned andrologist/endocrinologist and a clinical and basic investigator/educator.

Dr. Wang has been involved in many funded basic and clinical research studies. Her current clinical research studies include androgen replacement therapy, hormonal male contraceptive development, androgen metabolism, aging in men, and environment effects on sperm quality. She is the director of the CLIA licensed Endocrine and Metabolic Research Laboratory and developed state of the art measurements for steroid hormones. Her basic research studies are focused on the regulation of spermatogenesis and a XXY mouse model. The research spans from understanding the mechanisms of cellular action of hormones in the testis to physiological/pharmacological studies in vivo in rodent models. She is a world leader in efforts to develop a safe, effective, and reversible hormonal male contraceptive. As the former Chairperson of the Task Force Methods for the Regulation of Male Fertility of the World Health Organization (WHO), she designed many multicenter trials including the development and oversight of the pivotal study establishing the contraceptive efficacy of hormonally induced suppression of spermatogenesis. She is a co-director of the NICHD supported Contraceptive Clinical Trials Network Centers at . She was a chair and member of the expert group that edited the 3rd, 4th, most recently the 5th edition of the WHO Laboratory Manual on Semen Analyses, the gold standard for andrology laboratories throughout the world.

She has authored over 250 peer-reviewed publications, reviews and abstracts in endocrinology mainly on male reproductive biology including characterization of the pharmacokinetics and efficacy of androgens in men, trials of hormonal male contraceptive, regulation of germ cell apoptosis, and reproductive aging in the rat model. She edited a book on Male Reproductive Function and contributed many chapters in books on male reproduction, including Cecil's textbook of Medicine, Campbell's Urology, and the Leydig Cell. She is a recognized world leader on andrology and has been an invited keynote/ plenary/symposium speaker at many national and international conferences in andrology and endocrinology. She has been a superb role model and mentor for many students, endocrinologists and andrologists throughout her career. Supported by several NIH grants, she has aggressively advocated increased opportunities for women and minorities in biomedical research.

Dr. Wang had been Associate Editor of the International Journal of Andrology and served on the editorial board of the Journal of Andrology from 1994 to 1997. She is currently on the Editorial Board of Journal of Clinical Endocrinology and Metabolism. She has served on NIH study sections.

She served on many committees of the American Society of Andrology throughout the years. She was the Program Chair in 2005 and Vice President of the ASA from 2005-2006, President from 2006-2007, and Past President 2007-2008. Dr. Wang served on the Executive Committee of the International Society of Andrology from 1985 to 1989, Secretary 2001 to 2005, and chair of the Program Committee of the International Congress of Andrology 2005-2009. She is the current president of the International Society of Andrology (2009-2013).

Publications
Ilani Niloufar, Roth Mara Y, Amory John K, Swerdloff Ronald S, Dart Clint, Page Stephanie T, Bremner William J, Sitruk-Ware Regine, Kumar Narender, Blithe Diana L, Wang Christina, A new combination of testosterone and nestorone transdermal gels for male hormonal contraception. The Journal of clinical endocrinology and metabolism. 2012; 97(10): 3476-86.
Yin Anthony, Alfadhli Eman, Htun Michelle, Dudley Robert, Faulkner Sandra, Hull Laura, Leung Andrew, Bross Rachelle, Longstreth James, Swerdloff Ronald S, Wang Christina, Dietary Fat Modulates the Testosterone Pharmacokinetics of a New Self-Emulsifying Formulation of Oral Testosterone Undecanoate in Hypogonadal Men. Journal of andrology. 2012; 97(10): .
Surampudi Prasanth N, Wang Christina, Swerdloff Ronald, Hypogonadism in the aging male diagnosis, potential benefits, and risks of testosterone replacement therapy. International journal of endocrinology. 2012; 2012(1): 625434.
Ilani Niloufar, Armanious Nancy, Lue Yan-He, Swerdloff Ronald S, Baravarian Sima, Adler Alex, Tsang Christina, Jia Yue, Cui Yu-Gui, Wang Xing-Hai, Zhou Zuo-Min, Sha Jia-Hao, Wang Christina, Integrity of the blood-testis barrier in healthy men after suppression of spermatogenesis with testosterone and levonorgestrel. Human reproduction (Oxford, England). 2012; 97(10): .
Dusick Joshua R, Wang Christina, Cohan Pejman, Swerdloff Ronald, Kelly Daniel F, Pathophysiology of hypopituitarism in the setting of brain injury. Pituitary. 2012; 15(1): 2-9.
Yin Anthony Y, Htun Michelle, Swerdloff Ronald S, Diaz-Arjonilla Maruja, Dudley Robert E, Faulkner Sandra, Bross Rachelle, Leung Andrew, Baravarian Sima, Hull Laura, Longstreth James A, Kulback Steven, Flippo Gregory, Wang Christina, Reexamination of pharmacokinetics of oral testosterone undecanoate in hypogonadal men with a new self-emulsifying formulation. Journal of andrology. 2012; 33(2): 190-201.
Mendiola Jaime, Meeker John D, Jørgensen Niels, Andersson Anna-Maria, Liu Fan, Calafat Antonia M, Redmon J Bruce, Drobnis Erma Z, Sparks Amy E, Wang Christina, Hauser Russ, Swan Shanna H, Urinary concentrations of di(2-ethylhexyl) phthalate metabolites and serum reproductive hormones: pooled analysis of fertile and infertile men. Journal of andrology. 2012; 33(3): 488-98.
Ilani Niloufar, Liu Peter Y, Swerdloff Ronald S, Wang Christina, Does ethnicity matter in male hormonal contraceptive efficacy?. Asian journal of andrology. 2011; 13(4): 579-84.
Wang Christina, Ilani Niloufar, Arver Stefan, McLachlan Robert I, Soulis Tina, Watkinson Adam, Efficacy and safety of the 2% formulation of testosterone topical solution applied to the axillae in androgen-deficient men. Clinical endocrinology. 2011; 75(6): 836-43.
Wang Christina, Jackson Graham, Jones T Hugh, Matsumoto Alvin M, Nehra Ajay, Perelman Michael A, Swerdloff Ronald S, Traish Abdul, Zitzmann Michael, Cunningham Glenn, Low testosterone associated with obesity and the metabolic syndrome contributes to sexual dysfunction and cardiovascular disease risk in men with type 2 diabetes. Diabetes care. 2011; 34(7): 1669-75.
Ilani Niloufar, Swerdloff Ronald S, Wang Christina, Male hormonal contraception: potential risks and benefits. Reviews in endocrine & metabolic disorders. 2011; 12(2): 107-17.
Swerdloff Ronald S, Lue YanHe, Liu Peter Y, Erkkilä Krista, Wang Christina, Mouse model for men with klinefelter syndrome: a multifaceted fit for a complex disorder. Acta paediatrica (Oslo, Norway : 1992). 2011; 100(6): 892-9.
Amory John K, Bush Mark A, Zhi Hui, Caricofe Ralph B, Matsumoto Alvin M, Swerdloff Ronald S, Wang Christina, Clark Richard V, Oral testosterone with and without concomitant inhibition of 5α-reductase by dutasteride in hypogonadal men for 28 days. The Journal of urology. 2011; 185(2): 626-32.
Rothman Micol S, Carlson Nichole E, Xu Mei, Wang Christina, Swerdloff Ronald, Lee Paul, Goh Victor H H, Ridgway E Chester, Wierman Margaret E, Reexamination of testosterone, dihydrotestosterone, estradiol and estrone levels across the menstrual cycle and in postmenopausal women measured by liquid chromatography-tandem mass spectrometry. Steroids. 2011; 76(1-2): 177-82.
Swerdloff Ronald, Wang Christina, Testosterone treatment of older men--why are controversies created?. The Journal of clinical endocrinology and metabolism. 2011; 96(1): 62-5.
Wahjudi Paulin N, K Yee Jennifer, Martinez Steven R, Zhang Jin, Teitell Michael, Nikolaenko Liana, Swerdloff Ronald, Wang Christina, Lee W N Paul, Turnover of nonessential fatty acids in cardiolipin from the rat heart. Journal of lipid research. 2011; 52(12): 2226-33.
Ly Lam P, Sartorius Gideon, Hull Laura, Leung Andrew, Swerdloff Ronald S, Wang Christina, Handelsman David J, Accuracy of calculated free testosterone formulae in men. Clinical endocrinology. 2010; 73(3): 382-8.
Wagner Justin, Dusick Joshua R, McArthur David L, Cohan Pejman, Wang Christina, Swerdloff Ronald, Boscardin W John, Kelly Daniel F, Acute gonadotroph and somatotroph hormonal suppression after traumatic brain injury. Journal of neurotrauma. 2010; 27(6): 1007-19.
Mendiola Jaime, Jørgensen Niels, Andersson Anna-Maria, Calafat Antonia M, Ye Xiaoyun, Redmon J Bruce, Drobnis Erma Z, Wang Christina, Sparks Amy, Thurston Sally W, Liu Fan, Swan Shanna H, Are environmental levels of bisphenol a associated with reproductive function in fertile men?. Environmental health perspectives. 2010; 118(9): 1286-91.
Swerdloff Ronald S, Wang Christina, Dihydrotestosterone: hormone or autocrine--paracrine signal?. Annals of internal medicine. 2010; 153(10): 678-9.
de Paiva Neto Manoel Antonio, Vandergrift Alexander, Fatemi Nasrin, Gorgulho Alessandra A, Desalles Antonio A, Cohan Pejman, Wang Christina, Swerdloff Ronald, Kelly Daniel F, Endonasal transsphenoidal surgery and multimodality treatment for giant pituitary adenomas. Clinical endocrinology. 2010; 72(4): 512-9.
Liu Peter Y, Kalak Robert, Lue Yanhe, Jia Yue, Erkkila Krista, Zhou Hong, Seibel Markus J, Wang Christina, Swerdloff Ronald S, Dunstan Colin R, Genetic and hormonal control of bone volume, architecture, and remodeling in XXY mice. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2010; 25(10): 2148-54.
Liu Peter Y, Erkkila Krista, Lue YanHe, Jentsch J David, Schwarcz Monica Dorin, Abuyounes Deena, Hikim Amiya Sinha, Wang Christina, Lee Paul W-N, Swerdloff Ronald S, Genetic, hormonal, and metabolomic influences on social behavior and sex preference of XXY mice. American journal of physiology. Endocrinology and metabolism. 2010; 299(3): E446-55.
Wang Christina, Swerdloff Ronald S, Hormonal approaches to male contraception. Current opinion in urology. 2010; 20(6): 520-4.
Lue Yan-he, Wang Christina, Liu Peter Y, Erkilla Krista, Swerdloff Ronald S, Insights into the pathogenesis of XXY phenotype from comparison of the clinical syndrome with an experimental XXY mouse model. Pediatric endocrinology reviews : PER. 2010; 8 Suppl 1(1): 140-4.
Jia Yue, Lee Kuk-Wha, Swerdloff Ronald, Hwang David, Cobb Laura J, Sinha Hikim Amiya, Lue Yan He, Cohen Pinchas, Wang Christina, Interaction of insulin-like growth factor-binding protein-3 and BAX in mitochondria promotes male germ cell apoptosis. The Journal of biological chemistry. 2010; 285(3): 1726-32.
Lue YanHe, Swerdloff Ronald, Liu QingHai, Mehta Hemal, Hikim Amiya Sinha, Lee Kuk-Wha, Jia Yue, Hwang David, Cobb Laura J, Cohen Pinchas, Wang Christina, Opposing roles of insulin-like growth factor binding protein 3 and humanin in the regulation of testicular germ cell apoptosis. Endocrinology. 2010; 151(1): 350-7.
Wang Christina, Harnett Mark, Dobs Adrian S, Swerdloff Ronald S, Pharmacokinetics and safety of long-acting testosterone undecanoate injections in hypogonadal men: an 84-week phase III clinical trial. Journal of andrology. 2010; 31(5): 457-65.
Zhu Hui, Cui Yugui, Xie Jin, Chen Ling, Chen Xiangxiang, Guo Xuejiang, Zhu Yefei, Wang Xinghai, Tong Jiansun, Zhou Zuomin, Jia Yue, Lue Yan-He, Hikim Amiya Sinha, Wang Christina, Swerdloff Ronald S, Sha Jiahao, Proteomic analysis of testis biopsies in men treated with transient scrotal hyperthermia reveals the potential targets for contraceptive development. Proteomics. 2010; 10(19): 3480-93.
Liu Peter Y, Swerdloff Ronald S, Wang Christina, Recent methodological advances in male hormonal contraception. Contraception. 2010; 82(5): 471-5.
Gollenberg Audra L, Liu Fan, Brazil Charlene, Drobnis Erma Z, Guzick David, Overstreet James W, Redmon James B, Sparks Amy, Wang Christina, Swan Shanna H, Semen quality in fertile men in relation to psychosocial stress. Fertility and sterility. 2010; 93(4): 1104-11.
Jørgensen Niels, Liu Fan, Andersson Anna-Maria, Vierula Matti, Irvine D Stewart, Auger Jacques, Brazil Charlene K, Drobnis Erma Z, Jensen Tina K, Jouannet Pierre, Overstreet James W, Redmon J Bruce, Sparks Amy, Toppari Jorma, Wang Christina, Skakkebæk Niels E, Swan Shanna H, Serum inhibin-b in fertile men is strongly correlated with low but not high sperm counts: a coordinated study of 1,797 European and US men. Fertility and sterility. 2010; 94(6): 2128-34.
Cooper Trevor G, Noonan Elizabeth, von Eckardstein Sigrid, Auger Jacques, Baker H W Gordon, Behre Hermann M, Haugen Trine B, Kruger Thinus, Wang Christina, Mbizvo Michael T, Vogelsong Kirsten M, World Health Organization reference values for human semen characteristics. Human reproduction update. 2010; 16(3): 231-45.
Mahabadi Vahid, Amory John K, Swerdloff Ronald S, Bremner William J, Page Stephanie T, Sitruk-Ware Regine, Christensen Peter D, Kumar Narender, Tsong Yun-Yen, Blithe Diana, Wang Christina, Combined transdermal testosterone gel and the progestin nestorone suppresses serum gonadotropins in men. The Journal of clinical endocrinology and metabolism. 2009; 94(7): 2313-20.
Guo Jian, Jia Yue, Tao Shi-Xin, Li Yin-Chuan, Zhang Xue-Sen, Hu Zhao-Yuan, Chiang Naomi, Lue Yan-He, Hikim Amiya P Sinha, Swerdloff Ronald S, Wang Christina, Liu Yi-Xun, Expression of nitric oxide synthase during germ cell apoptosis in testis of cynomolgus monkey after testosterone and heat treatment. Journal of andrology. 2009; 30(2): 190-9.
Wang Christina, Nieschlag Eberhard, Swerdloff Ronald S, Behre Hermann, Hellstrom Wayne J, Gooren Louis J, Kaufman Jean M, Legros Jean-Jacques, Lunenfeld Bruno, Morales Alvaro, Morley John E, Schulman Claude, Thompson Ian M, Weidner Wolfgang, Wu Frederick C W, ISA, ISSAM, EAU, EAA and ASA recommendations: investigation, treatment and monitoring of late-onset hypogonadism in males. The aging male : the official journal of the International Society for the Study of the Aging Male. 2009; 12(1): 5-12.
Vesper Hubert W, Bhasin Shalender, Wang Christina, Tai Susan S, Dodge Larry A, Singh Ravinder J, Nelson Judie, Ohorodnik Susan, Clarke Nigel J, Salameh Wael A, Parker C Richard, Razdan Raj, Monsell Elizabeth A, Myers Gary L, Interlaboratory comparison study of serum total testosterone [corrected] measurements performed by mass spectrometry methods. Steroids. 2009; 74(6): 498-503.
Wang Christina, Nieschlag Eberhard, Swerdloff Ronald, Behre Hermann M, Hellstrom Wayne J, Gooren Louis J, Kaufman Jean M, Legros Jean-Jacques, Lunenfeld Bruno, Morales Alvaro, Morley John E, Schulman Claude, Thompson Ian M, Weidner Wolfgang, Wu Frederick C W, Wu Frederick C W, Wu Frederick C W, Wu Frederick C W, Wu Frederick C W, Wu Frederick C W, Investigation, treatment, and monitoring of late-onset hypogonadism in males: ISA, ISSAM, EAU, EAA, and ASA recommendations. European urology. 2009; 55(1): 121-30.
Lue YanHe, Wang Christina, Cui YuGui, Wang XingHai, Sha JiaHao, Zhou ZuoMin, Xu Jun, Wang Charles, Hikim Amiya P Sinha, Swerdloff Ronald S, Levonorgestrel enhances spermatogenesis suppression by testosterone with greater alteration in testicular gene expression in men. Biology of reproduction. 2009; 80(3): 484-92.
Jia Yue, Castellanos Jesse, Wang Christina, Sinha-Hikim Indrani, Lue Yanhe, Swerdloff Ronald S, Sinha-Hikim Amiya P, Mitogen-activated protein kinase signaling in male germ cell apoptosis in the rat. Biology of reproduction. 2009; 80(4): 771-80.
Wang Christina H, Rockhill Jason K, Mrugala Maciej, Peacock Danielle L, Lai Albert, Jusenius Katy, Wardlaw Joanna M, Cloughesy Timothy, Spence Alexander M, Rockne Russ, Alvord Ellsworth C, Swanson Kristin R, Prognostic significance of growth kinetics in newly diagnosed glioblastomas revealed by combining serial imaging with a novel biomathematical model. Cancer research. 2009; 69(23): 9133-40.
Bavisetty Sumati, Bavisetty Supriya, McArthur David L, Dusick Joshua R, Wang Christina, Cohan Pejman, Boscardin W John, Swerdloff Ronald, Levin Harvey, Chang Dongwoo J, Muizelaar Jan P, Kelly Daniel F, Chronic hypopituitarism after traumatic brain injury: risk assessment and relationship to outcome. Neurosurgery. 2008; 62(5): 1080-93; discussion 1093-4.
Liu Peter Y, Swerdloff Ronald S, Anawalt Bradley D, Anderson Richard A, Bremner William J, Elliesen Joerg, Gu Yi-Qun, Kersemaekers Wendy M, McLachlan Robert I, Meriggiola M Cristina, Nieschlag Eberhard, Sitruk-Ware Regine, Vogelsong Kirsten, Wang Xing-Hai, Wu Frederick C W, Zitzmann Michael, Handelsman David J, Wang Christina, Determinants of the rate and extent of spermatogenic suppression during hormonal male contraception: an integrated analysis. The Journal of clinical endocrinology and metabolism. 2008; 93(5): 1774-83.
Swerdloff Ronald S, Wang Christina, Free testosterone measurement by the analog displacement direct assay: old concerns and new evidence. Clinical chemistry. 2008; 54(3): 458-60.
Morgentaler Abraham, Dobs Adrian S, Kaufman Joel M, Miner Martin M, Shabsigh Ridwan, Swerdloff Ronald S, Wang Christina, Long acting testosterone undecanoate therapy in men with hypogonadism: results of a pharmacokinetic clinical study. The Journal of urology. 2008; 180(6): 2307-13.
Stokes-Riner Abbie, Thurston Sally W, Brazil Charlene, Guzick David, Liu Fan, Overstreet James W, Wang Christina, Sparks Amy, Redmon J Bruce, Swan Shanna H, One semen sample or 2? Insights from a study of fertile men. Journal of andrology. 2008; 28(5): 638-43.
Dusick Joshua R, Fatemi Nasrin, Mattozo Carlos, McArthur David, Cohan Pejman, Wang Christina, Swerdloff Ronald S, Kelly Daniel F, Pituitary function after endonasal surgery for nonadenomatous parasellar tumors: Rathke's cleft cysts, craniopharyngiomas, and meningiomas. Surgical neurology. 2008; 70(5): 482-90; discussion 490-1.
Fatemi Nasrin, Dusick Joshua R, Mattozo Carlos, McArthur David L, Cohan Pejman, Boscardin John, Wang Christina, Swerdloff Ronald S, Kelly Daniel F, Pituitary hormonal loss and recovery after transsphenoidal adenoma removal. Neurosurgery. 2008; 63(4): 709-18; discussion 718-9.
Cui Yugui, Zhu Hui, Zhu Yefei, Guo Xuejiang, Huo Ran, Wang Xinghai, Tong Jiansun, Qian Lixin, Zhou Zuomin, Jia Yue, Lue Yan-He, Hikim Amiya Sinha, Wang Christina, Swerdloff Ronald S, Sha Jiahao, Proteomic analysis of testis biopsies in men treated with injectable testosterone undecanoate alone or in combination with oral levonorgestrel as potential male contraceptive. Journal of proteome research. 2008; 7(9): 3984-93.
Johnson Candace, Jia Yue, Wang Christina, Lue Yan-He, Swerdloff Ronald S, Zhang Xue-Shen, Hu Zhao-Yuan, Li Yin-Chuan, Liu Yi-Xun, Hikim Amiya P Sinha, Role of caspase 2 in apoptotic signaling in primate and murine germ cells. Biology of reproduction. 2008; 79(5): 806-14.
Shiraishi Steve, Lee Paul W N, Leung Andrew, Goh Victor H H, Swerdloff Ronald S, Wang Christina, Simultaneous measurement of serum testosterone and dihydrotestosterone by liquid chromatography-tandem mass spectrometry. Clinical chemistry. 2008; 54(11): 1855-63.
Amory John K, Anawalt Bradley D, Matsumoto Alvin M, Page Stephanie T, Bremner William J, Wang Christina, Swerdloff Ronald S, Clark Richard V, The effect of 5alpha-reductase inhibition with dutasteride and finasteride on bone mineral density, serum lipoproteins, hemoglobin, prostate specific antigen and sexual function in healthy young men. The Journal of urology. 2008; 179(6): 2333-8.
Wang Christina, Shiraishi Steve, Leung Andrew, Baravarian Sima, Hull Laura, Goh Victor, Lee Paul W N, Swerdloff Ronald S, Validation of a testosterone and dihydrotestosterone liquid chromatography tandem mass spectrometry assay: Interference and comparison with established methods. Steroids. 2008; 73(13): 1345-52.
Aaltonen Pertti, Amory John K, Anderson Richard A, Behre Hermann M, Bialy Gabriel, Blithe Diana, Bone Wilhelm, Bremner William J, Colvard Doug, Cooper Trevor G, Elliesen Jörg, Gabelnick Henry L, Gu Yi-Qun, Handelsman David J, Johansson Elof A B, Kersemaekers Wendy, Liu Peter, MacKay Trent, Matlin Stephen, Mbizvo Michael, McLachlan Robert I, Meriggiola Maria Cristina, Mletzko Stephan, Mommers Ellen, Muermans Hilde, Nieschlag Eberhard, Odlind Viveca, Page Stephanie T, Radlmaier Albert, Sitruk-Ware Regine, Swerdloff Ronald, Wang Christina, Wu Frederick, Zitzmann Michael, 10th Summit Meeting consensus: recommendations for regulatory approval for hormonal male contraception. Journal of andrology. 2007; 28(3): 362-3.
Wang Christina, Christenson Peter, Swerdloff Ronald, Editorial: Clinical relevance of racial and ethnic differences in sex steroids. The Journal of clinical endocrinology and metabolism. 2007; 92(7): 2433-5.
Lue YanHe, Erkkila Krista, Liu Peter Y, Ma Kimberley, Wang Christina, Hikim Amiya Sinha, Swerdloff Ronald S, Fate of bone marrow stem cells transplanted into the testis: potential implication for men with testicular failure. The American journal of pathology. 2007; 170(3): 899-908.
Qoubaitary Ammar, Meriggiola Cristina, Ng Chiu Ming, Lumbreras Leslie, Cerpolini Silvia, Pelusi G, Christensen Peter D, Hull Laura, Swerdloff Ronald S, Wang Christina, Pharmacokinetics of testosterone undecanoate injected alone or in combination with norethisterone enanthate in healthy men. Journal of andrology. 2007; 27(6): 853-67.
Jia Yue, Hikim Amiya P Sinha, Lue Yan-He, Swerdloff Ronald S, Vera Yanira, Zhang Xue-Shen, Hu Zhao-Yuan, Li Yin-Chuan, Liu Yi-Xun, Wang Christina, Signaling pathways for germ cell death in adult cynomolgus monkeys (Macaca fascicularis) induced by mild testicular hyperthermia and exogenous testosterone treatment. Biology of reproduction. 2007; 77(1): 83-92.
Amory John K, Wang Christina, Swerdloff Ronald S, Anawalt Bradley D, Matsumoto Alvin M, Bremner William J, Walker Susan E, Haberer Lynda J, Clark Richard V, The effect of 5alpha-reductase inhibition with dutasteride and finasteride on semen parameters and serum hormones in healthy men. The Journal of clinical endocrinology and metabolism. 2007; 92(5): 1659-65.
Wang Christina, Cui Yu-Gui, Wang Xing-Hai, Jia Yue, Sinha Hikim Amiya, Lue Yan-He, Tong Jian-Son, Qian Li-Xin, Sha Jia-Hao, Zhou Zuo-Min, Hull Laura, Leung Andrew, Swerdloff Ronald S, transient scrotal hyperthermia and levonorgestrel enhance testosterone-induced spermatogenesis suppression in men through increased germ cell apoptosis. The Journal of clinical endocrinology and metabolism. 2007; 92(8): 3292-304.
Esposito Felice, Dusick Joshua R, Cohan Pejman, Moftakhar Parham, McArthur David, Wang Christina, Swerdloff Ronald S, Kelly Daniel F, Clinical review: Early morning cortisol levels as a predictor of remission after transsphenoidal surgery for Cushing's disease. The Journal of clinical endocrinology and metabolism. 2006; 91(1): 7-13.
Zhang Xue-Sen, Zhang Zhi-Hong, Jin Xuan, Wei Peng, Hu Xiao-Qian, Chen Min, Lu Cui-Ling, Lue Yan-He, Hu Zhao-Yuan, Sinha Hikim Amiya P, Swerdloff Ronald S, Wang Christina, Liu Yi-Xun, Dedifferentiation of adult monkey Sertoli cells through activation of extracellularly regulated kinase 1/2 induced by heat treatment. Endocrinology. 2006; 147(3): 1237-45.
Liu Peter Y, Wang Christina, Swerdloff Ronald S, Does individual response to androgen replacement therapy affect bone density?. Nature clinical practice. Endocrinology & metabolism. 2006; 2(2): 76-7.
Zhang Xue-Sen, Yuan Jin-Xiang, Liu Tao, Lue Yan-He, Jin Xuan, Tao Shi-Xin, Hu Zhao-Yuan, Hikim Amiya P Sinha, Swerdloff Ronald S, Wang Christina, Liu Yi-Xun, Expression of orphan receptors TR2, TR3, TR4, and p53 in heat-treated testis of cynomolgus monkeys (Macaca fascicularis). Journal of andrology. 2006; 27(3): 405-13.
Vera Yanira, Erkkilä Krista, Wang Christina, Nunez Concepcion, Kyttänen Sauli, Lue Yanhe, Dunkel Leo, Swerdloff Ronald S, Sinha Hikim Amiya P, Involvement of p38 mitogen-activated protein kinase and inducible nitric oxide synthase in apoptotic signaling of murine and human male germ cells after hormone deprivation. Molecular endocrinology (Baltimore, Md.). 2006; 20(7): 1597-609.
Wang Christina, Wang Xin Hai, Nelson Anita L, Lee Ka Kui, Cui Yu Gui, Tong Jian Sun, Berman Nancy, Lumbreras Leslie, Leung Andrew, Hull Laura, Desai Sagar, Swerdloff Ronald S, Levonorgestrel implants enhanced the suppression of spermatogenesis by testosterone implants: comparison between Chinese and non-Chinese men. The Journal of clinical endocrinology and metabolism. 2006; 91(2): 460-70.
Kelly Daniel F, McArthur David L, Levin Harvey, Swimmer Shana, Dusick Joshua R, Cohan Pejman, Wang Christina, Swerdloff Ronald, Neurobehavioral and quality of life changes associated with growth hormone insufficiency after complicated mild, moderate, or severe traumatic brain injury. Journal of neurotrauma. 2006; 23(6): 928-42.
Liu Peter Y, Swerdloff Ronald S, Christenson Peter D, Handelsman David J, Wang Christina, Wang Christina, Rate, extent, and modifiers of spermatogenic recovery after hormonal male contraception: an integrated analysis. Lancet. 2006; 367(9520): 1412-20.
Lue Yanhe, Wang Christina, Liu Yi-Xun, Hikim Amiya P Sinha, Zhang Xue-Sen, Ng Chiu-Ming, Hu Zhao-Yuan, Li Yin-Chuan, Leung Andrew, Swerdloff Ronald S, Transient testicular warming enhances the suppressive effect of testosterone on spermatogenesis in adult cynomolgus monkeys (Macaca fascicularis). The Journal of clinical endocrinology and metabolism. 2006; 91(2): 539-45.
Cohan Pejman, Wang Christina, McArthur David L, Cook Shon W, Dusick Joshua R, Armin Bob, Swerdloff Ronald, Vespa Paul, Muizelaar Jan Paul, Cryer Henry Gill, Christenson Peter D, Kelly Daniel F, Acute secondary adrenal insufficiency after traumatic brain injury: a prospective study. Critical care medicine. 2005; 33(10): 2358-66.
Qoubaitary Ammar, Swerdloff Ronald S, Wang Christina, Advances in male hormone substitution therapy. Expert opinion on pharmacotherapy. 2005; 6(9): 1493-506.
Veldhuis Johannes D, Bae Anthony, Swerdloff Ronald S, Iranmanesh Ali, Wang Christina, Experimentally induced androgen depletion accentuates ethnicity-related contrasts in luteinizing hormone secretion in asian and caucasian men. The Journal of clinical endocrinology and metabolism. 2005; 90(3): 1632-8.
Zhang Xue-Sen, Lue Yah-He, Guo Shu-Hua, Yuan Jin-Xiang, Hu Zhao-Yuan, Han Chun-Sheng, Hikim Amiya P Sinha, Swerdloff Ronald S, Wang Christina, Liu Yi-Xun, Expression of HSP105 and HSP60 during germ cell apoptosis in the heat-treated testes of adult cynomolgus monkeys (macaca fascicularis). Frontiers in bioscience : a journal and virtual library. 2005; 10(9): 3110-21.
Vera Yanira, Rodriguez Susana, Castanares Mark, Lue Yanhe, Atienza Vince, Wang Christina, Swerdloff Ronald S, Sinha Hikim Amiya P, Functional role of caspases in heat-induced testicular germ cell apoptosis. Biology of reproduction. 2005; 72(3): 516-22.
Qu Xiao-Dan, Gaw Gonzalo Irene T, Al Sayed Mohammed Y, Cohan Pejman, Christenson Peter D, Swerdloff Ronald S, Kelly Daniel F, Wang Christina, Influence of body mass index and gender on growth hormone (GH) responses to GH-releasing hormone plus arginine and insulin tolerance tests. The Journal of clinical endocrinology and metabolism. 2005; 90(3): 1563-9.
Hikim Amiya P Sinha, Vera Yanira, Vernet Dolores, Castanares Mark, Diaz-Romero Maruja, Ferrini Monica, Swerdloff Ronald S, Gonzalez-Cadavid Nestor F, Wang Christina, Involvement of nitric oxide-mediated intrinsic pathway signaling in age-related increase in germ cell apoptosis in male Brown-Norway rats. The journals of gerontology. Series A, Biological sciences and medical sciences. 2005; 60(6): 702-8.
Wang Christina, Catlin Don H, Starcevic Borislav, Heber David, Ambler Christie, Berman Nancy, Lucas Geraldine, Leung Andrew, Schramm Kathy, Lee Paul W N, Hull Laura, Swerdloff Ronald S, Low-fat high-fiber diet decreased serum and urine androgens in men. The Journal of clinical endocrinology and metabolism. 2005; 90(6): 3550-9.
Liu Peter Y, Wang Christina, Swerdloff Ronald S, Male sex matters. Clinical endocrinology. 2005; 63(6): 601-2.
Castanares Mark, Vera Yanira, Erkkilä Krista, Kyttänen Sauli, Lue Yanhe, Dunkel Leo, Wang Christina, Swerdloff Ronald S, Hikim Amiya P Sinha, Minocycline up-regulates BCL-2 levels in mitochondria and attenuates male germ cell apoptosis. Biochemical and biophysical research communications. 2005; 337(2): 663-9.
Hikim Amiya P Sinha, Vera Yanira, Elhag Rashid I, Lue Yanhe, Cui Yu-Gui, Pope Vanisha, Leung Andrew, Atienza Vince, Wang Christina, Swerdloff Ronald S, Mouse model of male germ cell apoptosis in response to a lack of hormonal stimulation. Indian journal of experimental biology. 2005; 43(11): 1048-57.
Liu Peter Y, Swerdloff Ronald S, Wang Christina, Relative testosterone deficiency in older men: clinical definition and presentation. Endocrinology and metabolism clinics of North America. 2005; 34(4): 957-72, x.
Bailey Janice, Evans Janice P, Hardy Matt, Herr John C, Loveland Kate, Matsumoto Alvin, Trasler Jacquetta, Turek Paul J, Vasquez-Levin Monica, Wang Christina, Wang Christina, Synopsis: 2005 annual meeting of the American Society of Andrology. Journal of andrology. 2005; 26(6): 678-88.
Chang Lisa, Harrington Darrell W, Milkotic Anton, Swerdloff Ronald S, Wang Christina, Unusual occurrence of extrapontine myelinolysis associated with acute severe hypernatraemia caused by central diabetes insipidus. Clinical endocrinology. 2005; 63(2): 233-5.
Lue Yanhe, Jentsch J David, Wang Christina, Rao P Nagesh, Hikim Amiya P Sinha, Salameh Wael, Swerdloff Ronald S, XXY mice exhibit gonadal and behavioral phenotypes similar to Klinefelter syndrome. Endocrinology. 2005; 146(9): 4148-54.
Swerdloff Ronald S, Wang Christina, Androgens and the ageing male. Best practice & research. Clinical endocrinology & metabolism. 2004; 18(3): 349-62.
Wang Christina, Cunningham Glenn, Dobs Adrian, Iranmanesh Ali, Matsumoto Alvin M, Snyder Peter J, Weber Thomas, Berman Nancy, Hull Laura, Swerdloff Ronald S, Long-term testosterone gel (AndroGel) treatment maintains beneficial effects on sexual function and mood, lean and fat mass, and bone mineral density in hypogonadal men. The Journal of clinical endocrinology and metabolism. 2004; 89(5): 2085-98.
Wang Christina, Swerdloff Ronald S, Male hormonal contraception. American journal of obstetrics and gynecology. 2004; 190(4 Suppl): S60-8.
Vera Yanira, Diaz-Romero Maruja, Rodriguez Susana, Lue Yanhe, Wang Christina, Swerdloff Ronald S, Sinha Hikim Amiya P, Mitochondria-dependent pathway is involved in heat-induced male germ cell death: lessons from mutant mice. Biology of reproduction. 2004; 70(5): 1534-40.
Wang Christina, Swerdloff Ronald, Kipnes Mark, Matsumoto Alvin M, Dobs Adrian S, Cunningham Glenn, Katznelson Laurence, Weber Thomas J, Friedman Theodore C, Snyder Peter, Levine Howard L, New testosterone buccal system (Striant) delivers physiological testosterone levels: pharmacokinetics study in hypogonadal men. The Journal of clinical endocrinology and metabolism. 2004; 89(8): 3821-9.
Brazil Charlene, Swan Shanna H, Tollner Charlene R, Treece Cathy, Drobnis Erma Z, Wang Christina, Redmon J Bruce, Overstreet James W, Overstreet James W, Quality control of laboratory methods for semen evaluation in a multicenter research study. Journal of andrology. 2004; 25(4): 645-56.
Brazil Charlene, Swan Shanna H, Drobnis Erma Z, Liu Fan, Wang Christina, Redmon J Bruce, Overstreet James W, Overstreet James W, Standardized methods for semen evaluation in a multicenter research study. Journal of andrology. 2004; 25(4): 635-44.
Wang Christina, Catlin Don H, Starcevic Borislav, Leung Andrew, DiStefano Emma, Lucas Geraldine, Hull Laura, Swerdloff Ronald S, Testosterone metabolic clearance and production rates determined by stable isotope dilution/tandem mass spectrometry in normal men: influence of ethnicity and age. The Journal of clinical endocrinology and metabolism. 2004; 89(6): 2936-41.
Ng Chiu Ming, Blackman Marc R, Wang Christina, Swerdloff Ronald S, The role of carnitine in the male reproductive system. Annals of the New York Academy of Sciences. 2004; 1033(3): 177-88.