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Isidro B. Salusky, M.D. [ Edit Your Profile ]

Work Email Address: isalusky@mednet.ucla.edu
Work Email Address: isalusky@pediatrics.medsch.ucla.edu

Work Phone Number: (310) 206-6987

Mailing Address:
BOX 951752, A2-373 MDCC
Los Angeles, CA 90095

Office Address:
200 UCLA Medical Plaza
Suite 265
Los Angeles, CA 90095

Work Address:
MDCC
Westwood, CA 90095

Work
CTSI Co-Chair, Participant and Clinical Interaction and Resources Program
UCLA Professor, Pediatrics Director, Clinical & Translational Research Laboratory Director, Hemodialysis and Peritoneal Dialysis Service Chief, Pediatric Nephrology
|reorganize| Director, General Clinical Research Center

Research Interests

Medicine - Nephrology; Pediatrics; Pediatrics - Pediatric


Education:
Degrees:
M.D., Medical School of Buenos Aires, Argentina, 1966 - 1971
B.S., Instit de Segunda Enseñanza, Argentina, 1959 - 1965
Fellowship:
1981 - 1982 UCLA School of Medicine
1979 - 1981 VA Wadsworth Medical Center, Los Angeles
1976 - 1979 Hospital Necker-Enfants Malades, Paris, France
Internship:
1972 - 1973 Pedro De Elizalde Hospital
Residency:
1972 - 1975 Pediatric Hosp Dr. Pedro de Elizade, Argentina

Certifications:
Certifications:
1991 American Board of Pediatrics
1989 American Board of Pediatrics
1981 - 1982 UCLA School of Medicine, Los Angeles

About

Dr. Salusky serves as Director of the Pediatric Dialysis Program at the UCLA Medical Center, and is a Professor of Pediatrics and Program Director of the General Clinical Research Center at UCLA School of Medicine. He earned his medical degree from the National University of Buenos Aires, and completed his residency at Dr. Pedro de Elizalde Hospital in Buenos Aires. He then completed a Pediatric Nephrology fellowship at Hospital des Enfants Malade in Paris, an advanced Research fellowship in Nutritional Metabolism at V.A. Wadsworth Medical Center in Los Angeles, and a Pediatric Nephrology fellowship at UCLA School of Medicine. Dr. Salusky was a Vice-Chair, for the K/DOQI Pediatric Guidelines, published by the National Kidney Foundation. He is a committee member of numerous pediatric nephrology societies, including the American Board of Pediatrics, American Society of Pediatric Nephrology, and the International Pediatric Nephrology Association. Dr. Salusky has authored over 100 peer-reviewed research publications, and over 200 abstracts. He is on the Editorial Board of American Journal of Kidney Diseases, Nephrologia Latino Americana, American Society of Nephrology, and Nephron.

Publications
Bacchetta Justine, Salusky Isidro B, Hewison Martin, Beyond mineral metabolism, is there an interplay between FGF23 and vitamin D in innate immunity?. Pediatric nephrology (Berlin, Germany). 2013; 28(4): 577-82.
Wesseling-Perry Katherine, Salusky Isidro B, Chronic kidney disease: mineral and bone disorder in children. Seminars in nephrology. 2013; 33(2): 169-79.
Li Jinnan, Molnar Miklos Z, Zaritsky Joshua J, Sim John J, Streja Elani, Kovesdy Csaba P, Salusky Isidro, Kalantar-Zadeh Kamyar, Correlates of parathyroid hormone concentration in hemodialysis patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2013; 28(2): .
Bacchetta Justine, Sea Jessica L, Chun Rene F, Lisse Thomas S, Wesseling-Perry Katherine, Gales Barbara, Adams John S, Salusky Isidro B, Hewison Martin, Fibroblast growth factor 23 inhibits extrarenal synthesis of 1,25-dihydroxyvitamin D in human monocytes. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2013; 28(1): 46-55.
Bacchetta Justine, Wesseling-Perry Katherine, Gilsanz Vicente, Gales Barbara, Pereira Renata C, Salusky Isidro B, Idiopathic juvenile osteoporosis: a cross-sectional single-centre experience with bone histomorphometry and quantitative computed tomography. Pediatric rheumatology online journal. 2013; 11(1): 6.
Griffin Lindsay M, Denburg Michelle R, Shults Justine, Furth Susan L, Salusky Isidro B, Hwang Wenke, Leonard Mary B, Nutritional vitamin D use in chronic kidney disease: a survey of pediatric nephrologists. Pediatric nephrology (Berlin, Germany). 2013; 28(2): 265-75.
Wesseling-Perry Katherine, Salusky Isidro B, Phosphate binders, vitamin D and calcimimetics in the management of chronic kidney disease-mineral bone disorders (CKD-MBD) in children. Pediatric nephrology (Berlin, Germany). 2013; 28(4): 617-25.
Bacchetta Justine, Wesseling-Perry Katherine, Kuizon Beatriz, Pereira Renata C, Gales Barbara, Wang He-Jing, Elashoff Robert, Salusky Isidro B, The skeletal consequences of growth hormone therapy in dialyzed children: a randomized trial. Clinical journal of the American Society of Nephrology : CJASN. 2013; 8(5): 824-32.
Miller Jessica E, Molnar Miklos Z, Kovesdy Csaba P, Zaritsky Joshua J, Streja Elani, Salusky Isidro, Arah Onyebuchi A, Kalantar-Zadeh Kamyar, Administered paricalcitol dose and survival in hemodialysis patients: a marginal structural model analysis. Pharmacoepidemiology and drug safety. 2012; 21(11): 1232-9.
Padhi Desmond, Langman Craig B, Fathallah-Shaykh Sahar, Warady Bradley A, Salusky Isidro B, Lee Edward, Wang Christine, Posvar Edward, An open-label study to evaluate a single-dose of cinacalcet in pediatric dialysis subjects. Pediatric nephrology (Berlin, Germany). 2012; 27(10): 1953-9.
Molnar Miklos Z, Kovesdy Csaba P, Mucsi Istvan, Salusky Isidro B, Kalantar-Zadeh Kamyar, Association of pre-kidney transplant markers of mineral and bone disorder with post-transplant outcomes. Clinical journal of the American Society of Nephrology : CJASN. 2012; 7(11): 1859-71.
Wesseling-Perry Katherine, Pereira Renata C, Tseng Chi-Hong, Elashoff Robert, Zaritsky Joshua J, Yadin Ora, Sahney Shobha, Gales Barbara, Jüppner Harald, Salusky Isidro B, Early skeletal and biochemical alterations in pediatric chronic kidney disease. Clinical journal of the American Society of Nephrology : CJASN. 2012; 7(1): 146-52.
Daugirdas John T, Chertow Glenn M, Larive Brett, Pierratos Andreas, Greene Tom, Ayus Juan Carlos, Kendrick Cynthia A, James Sam H, Miller Brent W, Schulman Gerald, Salusky Isidro B, Kliger Alan S, Kliger Alan S, Effects of frequent hemodialysis on measures of CKD mineral and bone disorder. Journal of the American Society of Nephrology : JASN. 2012; 23(4): 727-38.
Bacchetta Justine, Salusky Isidro B, Evaluation of hypophosphatemia: lessons from patients with genetic disorders. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2012; 59(1): 152-9.
Bacchetta Justine, Harambat Jérôme, Cochat Pierre, Salusky Isidro B, Wesseling-Perry Katherine, The consequences of chronic kidney disease on bone metabolism and growth in children. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2012; 27(8): 3063-71.
Bacchetta Justine, Cochat Pierre, Salusky Isidro B, Wesseling-Perry Katherine, Uric acid and IGF1 as possible determinants of FGF23 metabolism in children with normal renal function. Pediatric nephrology (Berlin, Germany). 2012; 27(7): 1131-8.
Wesseling-Perry Katherine, Tsai Eileen W, Ettenger Robert B, Jüppner Harald, Salusky Isidro B, Mineral abnormalities and long-term graft function in pediatric renal transplant recipients: a role for FGF-23?. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2011; 26(11): 3779-84.
Wesseling-Perry Katherine, Pereira Renata C, Sahney Shobha, Gales Barbara, Wang He-Jing, Elashoff Robert, Jüppner Harald, Salusky Isidro B, Calcitriol and doxercalciferol are equivalent in controlling bone turnover, suppressing parathyroid hormone, and increasing fibroblast growth factor-23 in secondary hyperparathyroidism. Kidney international. 2010; 25(10): .
Shimada Takashi, Urakawa Itaru, Isakova Tamara, Yamazaki Yuji, Epstein Michael, Wesseling-Perry Katherine, Wolf Myles, Salusky Isidro B, Jüppner Harald, Circulating fibroblast growth factor 23 in patients with end-stage renal disease treated by peritoneal dialysis is intact and biologically active. The Journal of clinical endocrinology and metabolism. 2010; 95(2): 578-85.
Jüppner Harald, Wolf Myles, Salusky Isidro B, FGF-23: More than a regulator of renal phosphate handling?. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2010; 25(10): 2091-7.
Zaritsky Joshua J, Salusky Isidro B, Ironing out the phosphorus problem. Kidney international. 2010; 77(10): 845-7.
Zaritsky Joshua, Young Brian, Gales Barbara, Wang He-Jing, Rastogi Anjay, Westerman Mark, Nemeth Elizabeta, Ganz Tomas, Salusky Isidro B, Reduction of serum hepcidin by hemodialysis in pediatric and adult patients. Clinical journal of the American Society of Nephrology : CJASN. 2010; 5(6): 1010-4.
Gonzalez Elsa, Schomberg John, Amin Nimisha, Salusky Isidro B, Zaritsky Joshua, Sevelamer carbonate increases serum bicarbonate in pediatric dialysis patients. Pediatric nephrology (Berlin, Germany). 2010; 25(2): 373-5.
Amin Nimisha, Gonzalez Elsa, Lieber Michael, Salusky Isidro B, Zaritsky Joshua J, Successful treatment of calcific uremic arteriolopathy in a pediatric dialysis patient. Pediatric nephrology (Berlin, Germany). 2010; 25(2): 357-62.
Wesseling-Perry Katherine, Harkins G Chris, Wang He-jing, Elashoff Robert, Gales Barbara, Horwitz Mara J, Stewart Andrew F, Jüppner Harald, Salusky Isidro B, The calcemic response to continuous parathyroid hormone (PTH)(1-34) infusion in end-stage kidney disease varies according to bone turnover: a potential role for PTH(7-84). The Journal of clinical endocrinology and metabolism. 2010; 95(6): 2772-80.
Rianthavorn Pornpimol, Ettenger Robert B, Salusky Isidro B, Kuizon Beatriz D, Trabecular bone volume and osteoprotegerin expression in uremic rats given high calcium. Pediatric nephrology (Berlin, Germany). 2010; 25(11): 2311-9.
Bakkaloglu Sevcan A, Wesseling-Perry Katherine, Pereira Renata C, Gales Barbara, Wang He-Jing, Elashoff Robert M, Salusky Isidro B, Value of the new bone classification system in pediatric renal osteodystrophy. Clinical journal of the American Society of Nephrology : CJASN. 2010; 5(10): 1860-6.
Langman Craig B, Alon Uri, Ingelfinger Julie, Englund Märta, Saland Jeffrey M, Somers Michael J G, Stapleton F Bruder, Sibú Nelson Orta, Cochat Pierre, Wong William, Eke Felicia U, Satlin Lisa, Salusky Isidro, A position statement on kidney disease from powdered infant formula-based melamine exposure in Chinese infants. Pediatric nephrology (Berlin, Germany). 2009; 24(7): 1263-6.
Mehrotra Rajnish, Kermah Dulcie A, Salusky Isidro B, Wolf Myles S, Thadhani Ravi I, Chiu Yi-Wen, Martins David, Adler Sharon G, Norris Keith C, Chronic kidney disease, hypovitaminosis D, and mortality in the United States. Kidney international. 2009; 76(9): 977-83.
Zaritsky Joshua, Young Brian, Wang He-Jing, Westerman Mark, Olbina Gordana, Nemeth Elizabeta, Ganz Tomas, Rivera Seth, Nissenson Allen R, Salusky Isidro B, Hepcidin--a potential novel biomarker for iron status in chronic kidney disease. Clinical journal of the American Society of Nephrology : CJASN. 2009; 4(6): 1051-6.
Wesseling-Perry Katherine, Salusky Isidro B, Is replacement therapy with nutritional and active forms of vitamin D required in chronic kidney disease mineral and bone disorder?. Current opinion in nephrology and hypertension. 2009; 18(4): 308-14.
Pereira Renata C, Juppner Harald, Azucena-Serrano Carlos E, Yadin Ora, Salusky Isidro B, Wesseling-Perry Katherine, Patterns of FGF-23, DMP1, and MEPE expression in patients with chronic kidney disease. Bone. 2009; 45(6): 1161-8.
Wesseling-Perry Katherine, Pereira Renata C, Wang Hejing, Elashoff Robert M, Sahney Shobha, Gales Barbara, Jüppner Harald, Salusky Isidro B, Relationship between plasma fibroblast growth factor-23 concentration and bone mineralization in children with renal failure on peritoneal dialysis. The Journal of clinical endocrinology and metabolism. 2009; 94(2): 511-7.
Wesseling-Perry Katherine, Harkins G Chris, Wang He-Jing, Sahney Shobha, Gales Barbara, Elashoff Robert M, Jüppner Harald, Salusky Isidro B, Response of different PTH assays to therapy with sevelamer or CaCO3 and active vitamin D sterols. Pediatric nephrology (Berlin, Germany). 2009; 24(7): 1355-61.
Wesseling Katherine, Bakkaloglu Sevcan, Salusky Isidro, Chronic kidney disease mineral and bone disorder in children. Pediatric nephrology (Berlin, Germany). 2008; 23(2): 195-207.
Zurowska Aleksandra, Feneberg Reinhard, Warady Bradley A, Zimmering Miriam, Monteverde Maria, Testa Sara, Calyskan Salim, Drozdz Dorota, Salusky Isidro, Kemper Markus J, Ekim Mesiha, Verrina Enrico, Misselwitz Joachim, Schaefer Franz, Gram-negative peritonitis in children undergoing long-term peritoneal dialysis. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2008; 51(3): 455-62.
Mehrotra Rajnish, Kermah Dulcie, Budoff Matthew, Salusky Isidro B, Mao Sang Shaou, Gao Yan Lin, Takasu Junichiro, Adler Sharon, Norris Keith, Hypovitaminosis D in chronic kidney disease. Clinical journal of the American Society of Nephrology : CJASN. 2008; 3(4): 1144-51.
Salusky Isidro B, Cohen Pinchas, Lost in translation?. Pediatric research. 2008; 64(3): 225.
Hernandez Joel D, Wesseling Katherine, Pereira Renata, Gales Barbara, Harrison Rick, Salusky Isidro B, Technical approach to iliac crest biopsy. Clinical journal of the American Society of Nephrology : CJASN. 2008; 3 Suppl 3(7): S164-9.
Zaritsky Joshua J, Salusky Isidro B, Gales Barbara, Ramos Georgina, Atkinson James, Allsteadt Amelia, Brandt Mary L, Goldstein Stuart L, Vascular access complications in long-term pediatric hemodialysis patients. Pediatric nephrology (Berlin, Germany). 2008; 23(11): 2061-5.
Wesseling Katherine, Salusky Isidro B, Vitamin D therapy in children on dialysis. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. 2008; 27(6): 651-3.
Greenbaum Larry A, Benador Nadine, Goldstein Stuart L, Paredes Ana, Melnick Joel Z, Mattingly Susan, Amdahl Michael, Williams Laura A, Salusky Isidro B, Intravenous paricalcitol for treatment of secondary hyperparathyroidism in children on hemodialysis. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2007; 49(6): 814-23.
Hernandez Joel D, Wesseling Katherine, Boechat M Ines, Gales Barbara, Salusky Isidro B, Osteomalacia in a hemodialysis patient receiving an active vitamin D sterol. Nature clinical practice. Nephrology. 2007; 3(4): 227-32.
Wesseling Katherine, Salusky Isidro B, Current treatment options in secondary hyperparathyroidism. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2006; 21(10): 2986-7; author reply 2989-90.
Chesney Russell W, Brewer Eileen, Moxey-Mims Marva, Watkins Sandra, Furth Susan L, Harmon William E, Fine Richard N, Portman Ronald J, Warady Bradley A, Salusky Isidro B, Langman Craig B, Gipson Debbie, Scheidt Peter, Feldman Harold, Kaskel Frederick J, Siegel Norman J, Report of an NIH task force on research priorities in chronic kidney disease in children. Pediatric nephrology (Berlin, Germany). 2006; 21(1): 14-25.
Hernandez Joel D, Wesseling Katherine, Salusky Isidro B, Role of parathyroid hormone and therapy with active vitamin D sterols in renal osteodystrophy. Seminars in dialysis. 2006; 18(4): 290-5.
Salusky Isidro B, Are new vitamin D analogues in renal bone disease superior to calcitriol?. Pediatric nephrology (Berlin, Germany). 2005; 20(3): 393-8.
Qiao Jian-Hua, Doherty Terence M, Fishbein Michael C, Salusky Isidro B, Luthringer Daniel L, Fitzpatrick Lorraine A, Shah Prediman K, Rajavashisth Tripathi B, Calcification of the coronary arteries in the absence of atherosclerotic plaque. Mayo Clinic proceedings. Mayo Clinic. 2005; 80(6): 807-9.
Greenbaum Larry A, Grenda Ryszard, Qiu Ping, Restaino Irene, Wojtak Amy, Paredes Ana, Benador Nadine, Melnick Joel Z, Williams Laura A, Salusky Isidro B, Intravenous calcitriol for treatment of hyperparathyroidism in children on hemodialysis. Pediatric nephrology (Berlin, Germany). 2005; 20(5): 622-30.
Salusky Isidro B, Goodman William G, Sahney Shobha, Gales Barbara, Perilloux Ashley, Wang He-Jing, Elashoff Robert M, Jüppner Harald, Sevelamer controls parathyroid hormone-induced bone disease as efficiently as calcium carbonate without increasing serum calcium levels during therapy with active vitamin D sterols. Journal of the American Society of Nephrology : JASN. 2005; 16(8): 2501-8.
Freundlich Michael, Jofe Michael, Goodman William G, Salusky Isidro B, Bone histology in steroid-treated children with non-azotemic nephrotic syndrome. Pediatric nephrology (Berlin, Germany). 2004; 19(4): 400-7.
Martin Kevin J, Olgaard Klaus, Coburn Jack W, Coen Giorgio M, Fukagawa Masafumi, Langman Craig, Malluche Hartmut H, McCarthy James T, Massry Shaul G, Mehls Otto, Salusky Isidro B, Silver Justin M, Smogorzewski Miroslaw T, Slatopolsky Eduardo M, McCann Linda, McCann Linda, Diagnosis, assessment, and treatment of bone turnover abnormalities in renal osteodystrophy. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2004; 43(3): 558-65.
Salusky Isidro B, Jüppner Harald, New PTH assays and renal osteodystrophy. Pediatric nephrology (Berlin, Germany). 2004; 19(7): 709-13.
Salusky Isidro B, Kuizon Beatriz G, Jüppner Harald, Special aspects of renal osteodystrophy in children. Seminars in nephrology. 2004; 24(1): 69-77.
Lima Eleonora M, Goodman William G, Kuizon Beatriz D, Gales Barbara, Emerick Aletha, Goldin Jonathan, Salusky Isidro B, Bone density measurements in pediatric patients with renal osteodystrophy. Pediatric nephrology (Berlin, Germany). 2003; 18(6): 554-9.
Oppenheim William L, Bowen Richard E, McDonough Paul W, Funahashi Tadashi T, Salusky Isidro B, Outcome of slipped capital femoral epiphysis in renal osteodystrophy. Journal of pediatric orthopedics. 2003; 23(2): 169-74.
Goodman William G, Jüppner Harald, Salusky Isidro B, Sherrard Donald J, Parathyroid hormone (PTH), PTH-derived peptides, and new PTH assays in renal osteodystrophy. Kidney international. 2003; 63(1): 1-11.
Mahdavi Homa, Kuizon Beatriz D, Gales Barbara, Wang He-Jing, Elashoff Robert M, Salusky Isidro B, Sevelamer hydrochloride: an effective phosphate binder in dialyzed children. Pediatric nephrology (Berlin, Germany). 2003; 18(12): 1260-4.
Salusky Isidro B, Goodman William G, Kuizon Beatriz D, Lavigne Jeffrey R, Zahranik Richard J, Gales Barbara, Wang He-Jing, Elashoff Robert M, Jüppner Harald, Similar predictive value of bone turnover using first- and second-generation immunometric PTH assays in pediatric patients treated with peritoneal dialysis. Kidney international. 2003; 63(5): 1801-8.
Lapeyraque Anne-Laure, Haddad Elie, André Jean-Luc, Brémond-Gignac Dominique, Taylor C Mark, Rianthavorn Pornpimol, Salusky Isidro B, Loirat Chantal, Sudden blindness caused by anterior ischemic optic neuropathy in 5 children on continuous peritoneal dialysis. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2003; 42(5): E3-9.
Salusky Isidro B, Goodman William G, Cardiovascular calcification in end-stage renal disease. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2002; 17(2): 336-9.
Kuizon Beatriz D, Salusky Isidro B, Cell biology of renal osteodystrophy. Pediatric nephrology (Berlin, Germany). 2002; 17(10): 777-89.
Chan James C M, Roth Karl S, Salusky Isidro B, Clinical research and training: an overview. The Journal of pediatrics. 2002; 140(3): 293-8.
Imanishi Yasuo, Tahara Hideki, Palanisamy Nallasivam, Spitalny Sarah, Salusky Isidro B, Goodman William, Brandi Maria Luisa, Drüeke Tilman B, Sarfati Emile, Ureña Pablo, Chaganti R S K, Arnold Andrew, Clonal chromosomal defects in the molecular pathogenesis of refractory hyperparathyroidism of uremia. Journal of the American Society of Nephrology : JASN. 2002; 13(6): 1490-8.
Sanchez Cheryl P, Kuizon Beatriz D, Goodman William G, Gales Barbara, Ettenger Robert B, Boechat M Inez, Wang Yang, Elashoff Robert, Salusky Isidro B, Growth hormone and the skeleton in pediatric renal allograft recipients. Pediatric nephrology (Berlin, Germany). 2002; 17(5): 322-8.
Goodman William G, Salusky Isidro B, Jüppner Harald, New lessons from old assays: parathyroid hormone (PTH), its receptors, and the potential biological relevance of PTH fragments. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2002; 17(10): 1731-6.
Salusky Isidro B, PTH assays in renal failure. Seminars in dialysis. 2002; 15(1): 73.