The goal of the proposed research is to create a bioinformatics program as part of the Clinical Translational Science Award. The Jonsson Comprehensive Cancer Center (JCCC) is a nationally recognized leader in translational research. As Director of Informatics for the JCCC, Dr. Arash Naeim oversees both strategic development and implementation efforts to support both research and clinical cancer systems at UCLA. He is overseeing the deployment of a clinical trial management system (Velos), an oncology specific electronic medical record system (Varian), and patient portal/web-based patient questionnaire system (Vision-Tree) as well as leading the JCCC's effort in testing and deploying caBIG tools within specific projects or spores. In addition, the JCCC informatics group works closely with pathology to integrate their biomaterial management system (Daedalus) with existing tissue banks and integration it with the CTMS.
From a research perspective, Dr. Naeim participates in both clinical trial and health services research with a specific focus and interest in older cancer patients. Research topics include: cost, cost-effectiveness, comparative effectiveness, comorbidity, frailty, decision-making, and outcomes research. He is the Site PI for a large multi-institutional study across all UC campuses focused on translational and comparative effectiveness research in breast cancer, which has a strong focus on developing informatics tools and platforms to accelerate research into patient care.
Administratively, Dr. Naeim reports to both the Cancer Center Director and the Hospital CIO. In this way, he is able to bridge the research and clinical needs in oncology. He also serves as the Chair of the Medical Staff Cancer Committee and is involved in policy and strategic decision across the hospital, cancer center, and Department of Medicine.
Given the need to build both a clinical research data repository and a research data repository, and ensure its utility in therapeutic and health services/comparative effectiveness research, Dr. Naeim's contribution will help ensure the CTSA is well-integrated with the cancer center and meets the needs of the research faculty. Lastly, his hope is to work with the Cancer Center and CTSA leadership to build a shared core that will serve as a foundation for our CTSA and also interlace with CTSA institutions.
Given his extensive experience working clinical data repository with the Cancer Center, Dr. Naeim is optimally qualified to co-lead the Data Repositories Workgroup of the Biomedical Informatics Program.