Dr. Katrina Dipple has an MD and a PhD in Biochemistry. She is a board certified clinical geneticist and clinical biochemical geneticist. In addition, she is a physician scientist who has an active research laboratory focused on understanding genetic disorders (primarily in inborn errors of metabolism and in craniofacial anomalies). She has extensive experience (publications) and funding for her research in metabolism, specifically the inborn error of metabolism, glycerol kinase deficiency; and has recently started a research program in understanding the genetics of craniofacial anomalies. She has over 20 years of research experience in genetics and molecular biology. In her role as a faculty member in Human Genetics, she has trained more than five postdoctoral fellows (two PhD, four MD), three PhD students, and numerous undergraduate students in the laboratory. In addition, she has served on the graduate committees of more than 10 graduate students at UCLA. Therefore, she is well poised to be on the faculty of this training grant.
Yang Xia, Deignan Joshua L, Qi Hongxiu, Zhu Jun, Qian Su, Zhong Judy, Torosyan Gevork, Majid Sana, Falkard Brie, Kleinhanz Robert R, Karlsson Jenny, Castellani Lawrence W, Mumick Sheena, Wang Kai, Xie Tao, Coon Michael, Zhang Chunsheng, Estrada-Smith Daria, Farber Charles R, Wang Susanna S, van Nas Atila, Ghazalpour Anatole, Zhang Bin, Macneil Douglas J, Lamb John R, Dipple Katrina M, Reitman Marc L, Mehrabian Margarete, Lum Pek Y, Schadt Eric E, Lusis Aldons J, Drake Thomas A,
Validation of candidate causal genes for obesity that affect shared
metabolic pathways and networks
MacLennan, N. K. Rahib, L. Shin, C. Fang, Z. Horvath, S. Dean, J. Liao, J. C. McCabe, E. R. Dipple, K. M.,
Targeted disruption of glycerol kinase gene in mice: expression analysis in liver shows alterations in network partners related to glycerol kinase activity
Hum Mol Genet.
Ohira, R.H., Dipple, K.M., Zhang, Y.-H., and McCabe, E.R.B.,
Human and murine glycerol kinase: Influence of exon 18 alternative splicing on function. Biochem. Biophys.
Cederbaum, S. D. Koo-McCoy, S. Tein, I. Hsu, B. Y. Ganguly, A. Vilain, E. Dipple, K. Cvitanovic-Sojat, L. Stanley, C.,
Carnitine membrane transporter deficiency: a long-term follow up and OCTN2 mutation in the first documented case of primary carnitine deficiency
Mol Genet Metab.
Ohira, R. Zhang, Y. H. Guo, W. Dipple, K. Shih, S. L. Doerr, J. Huang, B. L. Fu, L. J. Abu-Khalil, A. Geschwind, D. McCabe, E. R.,
Human ARX gene: genomic characterization and expression
Mol Genet Metab.
Dipple, KM Zhang, YH Huang, BL McCabe, LL Dallongeville, J Inokuchi, T Kimura, M Marx, HJ Roederer, GO Shih, V Yamaguchi, S Yoshida, I McCabe, ER,
Glycerol kinase deficiency: evidence for complexity in a single gene disorder
Human genetics. .
Zhang, Y Dipple, KM Vilain, E Huang, BL Finlayson, G Therrell, BL Worley, K Deininger, P McCabe, ER,
AluY insertion (IVS4-52ins316alu) in the glycerol kinase gene from an individual with benign glycerol kinase deficiency
Human mutation. .