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CTSI Directory

Laurie Ann Shaker-Irwin, M.Phil, Ph.D. [ Edit Your Profile ]

Email Address: lshakerirwin@mednet.ucla.edu

Office Phone Number: 310-794-7504

Office Address:
10833 Le Conte Ave.
CHS 14-143C
Los Angeles, CA 90095

UCLA Assistant Professor, Medicine

Ph.D., Yale University, 1989 - 1992
M.S., California State University, Northridge, 1983 - 1987
M.Phil, Yale University, 1987 - 1989
B.S., University of California, Los Angeles, 1979 - 1983


One of the main features of the Regulatory Knowledge and Support Program within the Clinical and Translational Science Institute (CTSI) is the Office of Investigator Services that facilitates and oversees CTSI research. Dr. Laurie Shaker-Irwin is the Director of the Facilitator Program, which serves as a point of entry for clinical research to be conducted within the CTSI. She will supervise and collaborate with several Research Facilitators on assuring that all investigators and their study teams know of and are able to access the breadth of clinical research resources at UCLA, through the use of one-to-one expert consultations, web portal access, educational and training opportunities, and ongoing personal guidance. She has the motivation, expertise, and knowledge to carry out the Director function. Her entire career has been dedicated to research with the last 25 years devoted to clinical research. Her experience spans many levels of involvement and therapeutic areas including the laboratory, field, hospital, and clinic. Just prior to coming to UCLA, she worked as the Executive Director at Pacific Oaks Research where she became an accomplished leader in expediting the approval of many new agents for HIV, while assuring the safety of research subjects, and the integrity of the research data. Shaker-Irwin came to UCLA in 2001 as the Research Subject Advocate (RSA) at the General Clinical Research Center where she oversaw hundreds of studies for ethics and compliance. She has made herself available to study teams for consultation on all aspects of clinical research from the ethical to the practical. She is a founding member and currently the President of the Society of Research Subject Advocates. She has excellent communication skills, supervised large numbers of individuals, and has organized several programs from their infancy, formulating a mission, and setting up systems and processes to prioritize and accomplish major goals. At UCLA, she is very familiar with the institutional policies, procedures, guidelines and resources available to conduct research at a large university. As a result of her knowledge, past experiences and service, she is highly suited to the Directorship role.

Justice A, Stein D, Fusco B, Sherrill J et al., Disease Progression in HIV-infected Patients Treated with Stavudine vs. Zidovudine. Journal of Clinical Epidemiology. 2004; 57: 89-97. (PMCID: 15019015) .
King J, Justice A, Roberts S, Chang C et al., Long-Term HIV/AIDS Survival Estimation in the Highly Active Antiretroviral Therapy Era. Medical Decision Making. 2003; 23: 9-20. (PMCID: 12583451) .
Korenman S & Shaker-Irwin L., Research Subject Advocacy – A New Way to Enhance Integrity in Clinical Research. Endocrine Society News . 2003; 6-7.
Becker et al., "Zidovudine and Stavudine Sequencing in HIV Treatment Planning: Findings from the Chorus HIV Cohort.". Journal of Acquired Immune Deficiency Syndromes. 2001; 26(1): 72-81 (PMCID: 11176271).
Shaker L., Shortening the Hospital Stay for Myocardial Infarction (letter). England Journal of Medicine. 1998; 319(15): 1021.
Powell L, Shaker L, Jones B, Vaccarino V, Thoreson C, Patillo J, "Psychosocial Predictors of Mortality in 83 Women with Premature Acute Myocardial Infarction.". Psychosomatic Medicine. 1993; 55: 426-433. (PMCID: 8265744).
Shaker L, Derycke-Chapman K, Brass L., "Using Pamphlets with Mail Surveys to Improve Response". American Journal of Public Health. 1992; 82(3): 463-464. (PMCID: 1536372).
Brass L & Shaker L., "Family History in Patients with Transient Ischemic Attacks.". Stroke. 1991; 2: 837-841. (PMCID: 1853402) .

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