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CTSI Directory

Timothy Donahue, M.D. [ Edit Your Profile ]

Work Email Address: tdonahue@mednet.ucla.edu

Fax Number: (310) 206-2472
Office Phone Number: (310) 206-7440
Work Phone Number: (310) 794-7788
(310) 825-9427

Mailing Address:
UCLA Surg-Gen Surg
BOX 956904
Los Angeles, CA 90095

Office Address:
10833 Le Conte Ave.
72-256 CHS
Los Angeles, CA 90095

UCLA Associate Professor, Surgery Associate Professor, General Surgery Associate Professor, Molecular & Medical Pharmacology

Research Interests

Molecular Biology, Pharmacology

M.D., Northwestern University Feinberg School of Medicine, 1998 - 2002
B.A., Northwestern University, 1998
2004 UCLA, Surgical Oncology Research Fellowship
2002 - 2004 UCLA School of Medicine
2006 - 2009 UCLA School of Medicine

2010 American Board of Surgery

Professional Societies:
2009 - 2009 Surgery

Certification Type:
2009 Molecular and Medical Pharmacology


Dr. Timothy Donahue is a surgeon scientist with a clinical practice and research program focused on pancreatic cancer. His laboratory is located in IMED and the JCCC. They are focused on the molecular genetics of pancreatic cancer with an overall goal of identifying better diagnostic markers, accurate predictive biomarkers, and targets for effective therapy. His position as a surgeon-scientist enables him to perform disease oriented translational research.

Nguyen Kovochich Anne, Arensman Michael, Lay Anna R, Rao Nagesh P, Donahue Timothy, Li Xinmin, French Samuel W, Dawson David W, HOXB7 promotes invasion and predicts survival in pancreatic adenocarcinoma. Cancer. 2013; 119(3): 529-39.
Nguyen Andrew H, Donahue Timothy R, Metastatic pancreatic insulinoma with treatment-limiting thrombocytopenia. The American surgeon. 2013; 79(3): E124-6.
Donald Graham W, Sunjaya Dharma, Lu Xuyang, Chen Formosa, Clerkin Barbara, Eibl Guido, Li Gang, Tomlinson James S, Donahue Timothy R, Reber Howard A, Hines Oscar J, Perioperative antibiotics for surgical site infection in pancreaticoduodenectomy: Does the SCIP-approved regimen provide adequate coverage?. Surgery. 2013; .
Hill Reginald, Li Yunfeng, Tran Linh M, Dry Sarah, Calvopina Joseph Hargan, Garcia Alejandro, Kim Christine, Wang Ying, Donahue Timothy R, Herschman Harvey R, Wu Hong, Cell intrinsic role of COX-2 in pancreatic cancer development. Molecular cancer therapeutics. 2012; 11(10): 2127-37.
Donahue Timothy R, Tran Linh M, Hill Reginald, Li Yunfeng, Kovochich Anne, Hargan Calvopina Joseph, Patel Sanjeet G, Wu Nanping, Hindoyan Antreas, Farrell James J, Li Xinmin, Dawson David W, Wu Hong, Integrative Survival-Based Molecular Profiling of Human Pancreatic Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2012; .
Donald Graham, Donahue Timothy, Reber Howard A, Hines O Joe, The evolving management of infected pancreatic necrosis. The American surgeon. 2012; 78(10): 1151-5.
Donahue Timothy R, Isacoff William H, Hines O Joe, Tomlinson James S, Farrell James J, Bhat Yasser M, Garon Edward, Clerkin Barbara, Reber Howard A, Downstaging chemotherapy and alteration in the classic computed tomography/magnetic resonance imaging signs of vascular involvement in patients with pancreaticobiliary malignant tumors: influence on patient selection for surgery. Archives of surgery (Chicago, Ill. : 1960). 2011; 146(7): 836-43.
Donahue Timothy R, Dawson David W, Nodal/Activin signaling: a novel target for pancreatic cancer stem cell therapy. Cell stem cell. 2011; 9(5): 383-4.
Donahue Timothy R, Reber Howard A, Operative blood loss and survival in pancreatic cancer. Pancreas. 2011; 40(1): 1-2.
Quatromoni Jon G, Morris Lilah F, Donahue Timothy R, Wang Yue, McBride William, Chatila Talal, Economou James S, T cell receptor transgenic lymphocytes infiltrating murine tumors are not induced to express foxp3. Journal of hematology & oncology. 2011; 4: 48.
Donahue Timothy R, Hines O Joe, Farrell James J, Tomlinson James S, Eibl Guido, Reber Howard A, Cystic neoplasms of the pancreas: results of 114 cases. Pancreas. 2010; 39(8): 1271-6.
Donahue Timothy R, Kattan Michael W, Nelson Scott D, Tap William D, Eilber Frederick R, Eilber Fritz C, Evaluation of neoadjuvant therapy and histopathologic response in primary, high-grade retroperitoneal sarcomas using the sarcoma nomogram. Cancer. 2010; 116(16): 3883-91.
Donahue Timothy R, Kazanjian Kevork K, Isacoff William H, Reber Howard A, Hines O Joe, Impact of splenectomy on thrombocytopenia, chemotherapy, and survival in patients with unresectable pancreatic cancer. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 2010; 14(6): 1012-8.
Hill Reginald, Calvopina Joseph Hargan, Kim Christine, Wang Ying, Dawson David W, Donahue Timothy R, Dry Sarah, Wu Hong, PTEN loss accelerates KrasG12D-induced pancreatic cancer development. Cancer research. 2010; 70(18): 7114-24.
Donahue Timothy R, Reber Howard A, Pancreatic surgery. Current opinion in gastroenterology. 2010; 26(5): 499-505.
Donahue Timothy, Hines O Joe, The ZIP4 pathway in pancreatic cancer. Cancer biology & therapy. 2010; 9(3): 243-5.
Donahue Timothy R, Hines O Joe, CXCR2 and RET single nucleotide polymorphisms in pancreatic cancer. World journal of surgery. 2009; 33(4): 710-5.
Vo Dan D, Prins Robert M, Begley Jonathan L, Donahue Timothy R, Morris Lilah F, Bruhn Kevin W, de la Rocha Pilar, Yang Meng-Yin, Mok Stephen, Garban Hermes J, Craft Noah, Economou James S, Marincola Francesco M, Wang Ena, Ribas Antoni, Enhanced antitumor activity induced by adoptive T-cell transfer and adjunctive use of the histone deacetylase inhibitor LAQ824. Cancer research. 2009; 69(22): 8693-9.
Ribas Antoni, Comin-Anduix Begoña, Economou James S, Donahue Timothy R, de la Rocha Pilar, Morris Lilah F, Jalil Jason, Dissette Vivian B, Shintaku Itsushi Peter, Glaspy John A, Gomez-Navarro Jesus, Cochran Alistair J, Intratumoral immune cell infiltrates, FoxP3, and indoleamine 2,3-dioxygenase in patients with melanoma undergoing CTLA4 blockade. Clinical cancer research : an official journal of the American Association for Cancer Research. 2009; 15(1): 390-9.
Donahue Timothy R, Hiatt Jonathan R, Busuttil Ronald W, Collagenase and surgical disease. Hernia : the journal of hernias and abdominal wall surgery. 2006; 10(6): 478-85.